HUMAN IPSC-DERIVED ASTROCYTES GENERATED FROM DONORS WITH GLOBOID CELL LEUKODYSTROPHY DISPLAY PHENOTYPES ASSOCIATED WITH DISEASE

Human iPSC-derived astrocytes generated from donors with globoid cell leukodystrophy display phenotypes associated with disease

Globoid cell leukodystrophy (Krabbe disease) is a fatal neurodegenerative, demyelinating disease Horse Reins caused by dysfunctional activity of galactosylceramidase (GALC), leading to the accumulation of glycosphingolipids including psychosine.While oligodendrocytes have been extensively studied due to their high levels of GALC, the contribution o

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Music Lyrics and Influence on Teen Sex

“As a baby boomer, I was part of the generation that grew up with rock and roll.I recall the first time I heard my mother respond to explicit lyrics my older brother was listening Urn Necklace to and thinking what a renegade he was.They weren’t nearly as explicit as the lyrics of today’s music, and while I swore that I’d never become my mot

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Exogenous estradiol enhances apoptosis in regressing post-partum rat corpora lutea possibly mediated by prolactin

Abstract Background In pregnant rats, structural luteal regression takes place after parturition and is associated with cell death by apoptosis.We have recently shown that the hormonal environment is responsible for the fate of the corpora lutea (CL).Changing the levels of circulating hormones in post-partum rats, either by injecting androgen, Urn

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